Mechanisms of Action and Predictors of Outcome

Research evaluating mechanisms of action aims to identify the variables or processes through which a treatment produces a change in desired outcomes.

Research evaluating predictors of outcome aims to identify variables that are associated with better or worse treatment outcomes.

Research Trials

*Listed in reverse chronological order

McMain, SF, Fitzpatrick, S, Boritz, T, Barnhart, R, Links, P, and Streiner, DL. (2017). Outcome trajectories and prognostic factors for suicide and self-harm behaviors in patients with borderline personality disorder following one year of outpatient psychotherapy. Journal of Personality Disorders.

Steuwe, C, Berg, M, Driessen, M, and Beblo, T. (2017). Impact of therapist change after initial contact and traumatic burden on dropout in a naturalistic sample of inpatients with borderline pathology receiving dialectical behavior therapy. Borderline Personality Disorder and Emotion Dysregulation, 4.

Landes, SJ, Chalker, SA, Comtois, KA. (2016). Predicting dropout in outpatient dialectical behavior therapy with patients with borderline personality disorder receiving psychiatric disability. Borderline Personality Disorder and Emotion Dysregulation, 3.

Kleindienst, N, Priebe, K, Görg, N, Dyer, A, Steil, R, et al. (2016). State dissociation moderates response to dialectical behavior therapy for posttraumatic stress disorder in women with and without borderline personality disorder. European Journal of Psychotraumatology, 7.

Schmitt, R, Winter, D, Niedtfeld, I, Herpertz, SC, Schmahl, C. (2016). Effects of psychotherapy on neuronal correlates of reappraisal in female patients with borderline personality disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1, 548-557.

Barnicot, K, Gonzalez, R, McCabe, R, Priebe, S. (2016). Skills use and common treatment processes in dialectical behaviour therapy for borderline personality disorder. Journal of Behavior Therapy and Experimental Psychiatry, 52, 147-156.

Winter, D., Niedtfeld, I., Schmitt, R. et al. (2016). Neural correlates of distraction in borderline personality disorder before and after dialectical behavior therapy. European Archives of Psychiatry and Clinical Neuroscience.

Ruocco, AC, Rodrigo, AH, McMain, SF, Page-Gould, E, Ayaz, H, & Links, PS (2016). Predicting treatment outcomes from prefrontal cortex activation for self-harming patients with borderline personality disorder: A preliminary study. Frontiers in Human Neuroscience, 10, 220.

Wilks, CR, Korslund, KE, Harned, MH, & Linehan, MM (2016). Dialectical behavior therapy and domains of functioning over two years. Behaviour Research and Therapy, 77, 162-169.

Kramer, U, Pascual-Leone, A, Berthoud, L, De Roten, Y, Marquet, P, Kolly, S, Despland, JN, & Page, D (2016). Assertive anger mediates effects of dialectical behaviour-informed skills training for borderline personality disorder: A randomized controlled trial. Clinical Psychology & Psychotherapy, 23, 189-202.

Bedics, JD, Atkins, DC, Harned, MS, & Linehan, MM (2015). The therapeutic alliance as a predictor of outcome in dialectical behavior therapy versus nonbehavioral psychotherapy by experts for borderline personality disorder. Psychotherapy, 52, 67-77.

Neacsiu, AD, Eberle, JW, Kramer, R, Wiesmann, T, & Linehan, MM. (2014) Dialectical behavior therapy skills for transdiagnostic emotion dysregulation: A pilot randomized controlled trial. Behaviour Research and Therapy, 59, 40-51.

Axelrod, SR, Perepletchikova, F, Holtzman, K, & Sinha, R (2011). Emotion regulation and substance use frequency in women with substance dependence and borderline personality disorder receiving dialectical behavior therapy. American Journal of Drug and Alcohol Abuse, 37, 37-42.

Neacsiu, AD, Rizvi, SL, & Linehan, MM (2010). Dialectical behavior therapy skills use as a mediator and outcome of treatment for borderline personality disorder. Behaviour Research and Therapy, 48, 832-839.

Berking, M., Neacsiu, A., Comtois, KA, & Linehan, MM (2009). The impact of experiential avoidance on the reduction of depression in treatment for borderline personality disorder. Behaviour Research and Therapy, 47, 663-670.